| Seed | West | South | Midwest | East |
|---|---|---|---|---|
| 1 | Arizona | Duke | Michigan | UConn |
| 2 | Gonzaga | Iowa State | Nebraska | Illinois |
| 3 | Houston | Vanderbilt | Purdue | Michigan State |
| 4 | BYU | Florida | Texas Tech | Virginia |
| 5 | Kansas | Alabama | Arkansas | UNC |
| 6 | Tennessee | St. John's | Louisville | Clemson |
| 7 | Saint Louis | Auburn | Kentucky | SMU |
| 8 | Villanova | UCF | Iowa | Texas A&M |
| 9 | Georgia | NC State | Wisconsin | St. Mary's |
| 10 | Utah State | USC | Miami (FL) | Miami (OH) |
| 11 | Indiana | UCLA | Ohio State/Texas | San Diego State/Virginia Tech |
| 12 | Tulsa | Belmont | Yale | Liberty |
| 13 | Stephen F. Austin | High Point | Utah Valley | UNCW |
| 14 | Hawaii | Troy | ETSU | North Dakota State |
| 15 | Portland State | Wright State | Austin Peay | Navy |
| 16 | Tennessee-Martin | Merimack | Vermont/Maryland Eastern Shore | Long Island/Bethune Cookman |